Which of the following is likely to have elevated blood pressure when combined?

The combination of Ritalin, which is a stimulant medication, and LSD, a hallucinogen, is likely to result in elevated blood pressure. Ritalin (methylphenidate) acts by increasing levels of certain neurotransmitters in the brain, particularly dopamine and norepinephrine, which can cause stimulation of the cardiovascular system. This can lead to increased heart rate and elevated blood pressure. When combined with LSD, which can also influence autonomic functions and has the potential to cause physiological effects like increased heart rate and blood vessel dilation, the combined stimulatory effects can exacerbate these cardiovascular responses, leading to significant increases in blood pressure.

In contrast, alcohol tends to depress the central nervous system and may not necessarily lead to elevated blood pressure in combination with Blotter Acid. Synthetic cannabinoids and fentanyl pose more risks related to severe respiratory depression rather than elevated blood pressure. The combination of cocaine and MDMA, while potentially harmful, is generally associated with increased heart rates and could elevate blood pressure, but the strong stimulant effects of both are not as directly comparable to the Ritalin and LSD pairing, where both agents distinctly push up blood pressure through their action on the cardiovascular system.